DPYD Test Purpose
DPYD testing analyses variants in the DPYD gene which encodes the dihydropyrimidine dehydrogenase (DPD) enzyme, responsible for metabolising 5-FU and capecitabine. Individuals with deficient or reduced DPD enzyme activity are at risk of increased toxicity with these medications.
DPYD testing can assist with identifying individuals at risk of toxicity, allowing the doctor to personalise treatment plans by adjusting the dose
or considering an alternative medication.
myDNA’s NATA accredited laboratory performs pharmacogenomic testing to detect the following DPYD variants:
*13 (c1679T>G)
*2A (c1905+1G>A)
c.2846A>T
c.1129‐5923C>G
c.557A>G
How it works
We provide buccal test kits to your clinic at no charge, ready for sample collection.
Buccal kit includes a buccal swab, request form, instructions regarding sample collection, and an express prepaid return envelope
Step 1
Collect patient’s buccal sample during their consultation.
Step 2
Complete the request form and ask the patient to fill in their credit card details on the back.
Step 3
Place collected sample and completed request form inside the express prepaid return envelope and send back to our lab.
Step 4
Requesting the Test Kit:
Ordering
To order the DPYD Test kits, please contact our customer service team:
P: 1300 463 373
Sample Required:
Buccal
(Results from a buccal swab sample are equally reliable to results from a blood sample)
Turnaround Time:
DPYD results are available within 3 days on sample receipt.
Cost to Patient:
DPYD Test is priced at $160.
DPYD/UGT1A1 Combined Test is priced at $250.
Please note that this test is not eligible for Medicare rebates.
Clinical Team
The myDNA clinical team consists of qualified clinical geneticists, pharmacists and pharmacologists with expertise in the clinical application of pharmacogenomics.
The team is available to discuss results. Simply call us on 1300 436 373.
Downloadable Resources
DPYD Brochure
DPYD Request Form
Enquire Here
For further information please provide your details and we will respond within 2 business days.
Patient Privacy and Security
All DNA remains the property of the patient. DNA samples are de-identified upon arrival at our laboratory to ensure all DNA remains anonymous, and our DNA analysis technique cannot be used to identify individuals or their relatives. myDNA will never share any patient data with third parties without written consent and uses secure encrypted servers to protect it.